Entry Level
8 analog or 24 digital lines · 12/14-bit · up to 48 kS/s · No external supply needed
View detailsUp to 1.25 MS/s · 24-bit IEPE
High Performance
The top of the range. M-series modules sampling to 1.25 MS/s with as many as 80 analog inputs and 48 digital lines, alongside 24-bit IEPE instruments with built-in signal conditioning for accelerometers and microphones.
- 4–80 channels · 16/24-bit
- Up to 1.25 MS/s
- Built-in IEPE conditioning
Product views
Front and top views of the module. Enclosure, terminal style and silkscreen vary by model — confirm the exact part number before ordering.
Why this tier
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The fastest tier, by a factor of three
The 6251, 6259 and 6255 sample a single channel at 1.25 MS/s — three times the multifunction tier — while keeping 16-bit resolution across the board.
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Up to 80 analog inputs
When the limit is channel count rather than sample rate, the 6225 and 6255 put 80 inputs on one module, with 24 digital lines alongside.
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A dynamic signal analyser in a laptop bag
The USB-4431 and USB-4432 carry 24-bit resolution, built-in IEPE conditioning and anti-alias filtering, so accelerometers and microphones connect directly with no separate signal conditioner on the rack.
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Four simultaneous analog outputs
The USB-6229 updates all four of its 16-bit outputs at 833 kS/s simultaneously — enough to drive a shaker, a servo valve and two reference signals at once.
Models in this tier
All models share the same driver and software support. Terminal options vary — check the Terminal column in the table below.
| Model | Analog input | Resolution | Max sample rate | Analog output | Digital I/O | Counters | Terminal |
|---|---|---|---|---|---|---|---|
| USB-4431Four 24-bit IEPE inputs and one analog output for shaker drive. | 4 DI | 24-bit | 102.4 kS/s | 1 × 24-bit | — | — | BNC per channel |
| USB-4432A fifth input channel and a wider ±40 V range — though only the first four channels carry IEPE conditioning. | 5 DI | 24-bit | 102.4 kS/s | — | — | — | BNC per channel |
| USB-622116 inputs, 2 outputs, 24 digital lines — the small end of the 62xx family. | 16 SE / 8 DI | 16-bit | 250 kS/s | 2 × 16-bit | 24 | 2 × 32-bit, 80 MHz | Screw terminal / OEM |
| USB-622932 inputs with four simultaneous analog outputs — the control-and-measure workhorse. | 32 SE / 16 DI | 16-bit | 250 kS/s | 4 × 16-bit | 48 | 2 × 32-bit, 80 MHz | Screw terminal / mass termination |
| USB-622580 analog inputs on the 250 kS/s platform — the widest count for the money. | 80 SE / 40 DI | 16-bit | 250 kS/s | 2 × 16-bit | 24 | 2 × 32-bit, 80 MHz | Mass termination / screw terminal |
| USB-625116 inputs at 1.25 MS/s with two fast 16-bit outputs — the M-series step up from the 6212. | 16 SE / 8 DI | 16-bit | 1.25 MS/s | 2 × 16-bit | 24 | 2 × 32-bit, 80 MHz | Mass termination / screw terminal |
| USB-625932 inputs and four fast outputs — the widest control-and-measure module at 1.25 MS/s. | 32 SE / 16 DI | 16-bit | 1.25 MS/s | 4 × 16-bit | 48 | 2 × 32-bit, 80 MHz | Mass termination / screw terminal |
| USB-6255The same 80 channels as the 6225, at five times the sample rate. | 80 SE / 40 DI | 16-bit | 1.25 MS/s | 2 × 16-bit | 24 | 2 × 32-bit, 80 MHz | Mass termination / screw terminal |
Swipe the table sideways to see all columns
Specifications
Analog input
| Channels | 4 IEPE (USB-4431) · 5, of which 4 IEPE (USB-4432) · 16 (USB-6221, USB-6251) · 32 (USB-6229, USB-6259) · 80 (USB-6225, USB-6255) |
|---|---|
| Resolution | 24-bit (USB-4431/4432) · 16-bit (M-series) |
| Max sample rate | 1.25 MS/s (USB-6251/6259/6255) · 250 kS/s (USB-6221/6225/6229) · 102.4 kS/s (USB-4431/4432) |
| Input ranges | ±10 V, ±5 V, ±1 V, ±0.2 V (M-series) · ±10 V on the USB-4431, ±40 V on the USB-4432, AC or DC coupling selectable per channel |
| IEPE conditioning | Built in on the USB-4431 / 4432, 0 or 2.1 mA constant current per channel |
| Anti-alias filter | Automatic on the USB-4431 / 4432 |
Analog output
| Channels | 1 (USB-4431 only — the USB-4432 has none) · 2 (USB-6221, USB-6225, USB-6251, USB-6255) · 4 (USB-6229, USB-6259) |
|---|---|
| Resolution | 24-bit (USB-4431) · 16-bit (M-series) |
| Update rate | 2.86 MS/s (USB-6251/6259/6255) · 833 kS/s (USB-6221/6225/6229) · 96 kS/s (USB-4431) |
| Output range | ±10 V · ±3.5 V on the USB-4431 |
Digital I/O and counters
| Digital lines | 24 (USB-6221, USB-6225, USB-6251, USB-6255) · 48 (USB-6229, USB-6259) · none on the IEPE parts |
|---|---|
| Logic level | 5 V TTL / CMOS compatible |
| Counters | 2 × 32-bit, 80 MHz on the M-series · none on the IEPE parts |
Bus, power and physical
| Bus | USB 2.0 high speed |
|---|---|
| Power | USB bus powered; external supply recommended for the 80-channel modules |
| Terminal | Mass termination or screw terminal · BNC per channel on the USB-4431 / 4432 |
| Mounting | DIN-rail or rack mount kit |
| Dimensions | See datasheet |
Environment and compliance
| Operating temperature | 0 to 45 °C |
|---|---|
| Storage temperature | −40 to 70 °C |
| Compliance | CE · FCC · RoHS |
| Warranty | 2 years |
Specifications are summarised for selection purposes. Always confirm against the current datasheet for the exact part number before design freeze.
Typical use cases
- Vibration, NVH and modal analysis
- Acoustic and microphone array measurement
- High-channel-count structural test
- Closed-loop control and shaker drive
Software & drivers
One driver covers the whole range. Install it once and every model on this page appears in Measurement & Automation Explorer.
- NI-DAQmx compatible driver
- LabVIEW
- Python (nidaqmx)
- C / C++
- C# / .NET
- MATLAB
Wiring & pinout
Pinout drawings and connector definitions are in the download section, together with sample code for every supported language.
Pinouts & CADDownloads for this tier
- High performance datasheet — USB-4431 / 4432 / 6221 / 6225 / 6229 / 6251 / 6255 / 6259 Request
Other tiers
Low Cost
8 SE / 4 DI · 14 or 16-bit · 20 / 50 / 100 kS/s · 13 DIO · or 96 on the 6509
View detailsMultifunction
16–32 SE · 16-bit · 250–400 kS/s · 8–32 DIO · 2 counters
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